The CFRI CF Community Voices Podcast

Five Feet Apart Discussion 4 - Medical Inaccuracies (Audio)

CFRI hosted an online Town Hall Discussion on the film "Five Feet Apart," during which participants from around the U.S. joined in via Zoom. The discussion was broken into five topics. The full recording is available on our YouTube CF Community Voices playlist, but in this fourth episode, as "CF insiders" we explore what drove us a bit crazy in terms of medical inaccuracies in the film.

Sponsored by Vertex Pharmaceuticals, Gilead Sciences and Chiesi USA.

Five Feet Apart Discussion 3 - Risk Taking (Audio)

CFRI hosted an online Town Hall Discussion on the film "Five Feet Apart," during which participants from around the U.S. joined in via Zoom. The discussion was broken into five topics. The full recording is available on our YouTube CF Community Voices playlist, but in this third episode, we explore what type of message the "stealing a foot from CF" sends to the CF community.

Sponsored by Vertex Pharmaceuticals, Gilead Sciences and Chiesi USA.

Five Feet Apart Town Hall - Portrayal of CF Audio

CFRI hosted an online Town Hall Discussion on the film "Five Feet Apart," during which participants from around the U.S. joined in via Zoom. The discussion was broken into five topics. The full recording is available on our CF Community Voices playlist, but in this second episode, we explore the portrayal of the those with CF in the film.

Sponsored by Vertex Pharmaceuticals, Gilead Sciences and Chiesi USA.

Five Feet Apart Discussion - Impact of Film (Audio)

CFRI hosted an online Town Hall Discussion on the film "Five Feet Apart," during which participants from around the U.S. joined in via Zoom. The discussion was broken into five topics. The full recording is available on our CF Community Voices playlist, but in this first episode, we explore the impact of the film upon the general public and the CF community.

Sponsored by Vertex Pharmaceuticals, Gilead Sciences and Chiesi USA.

Five Feet Apart Town Hall Discussion - Full Audio

CFRI hosted an online Town Hall Discussion on the film "Five Feet Apart," during which participants from around the U.S. joined in via Zoom to share their opinions and feelings about key themes of the movie.

Sponsored by Vertex Pharmaceuticals, Gilead Sciences and Chiesi USA.

CFTR, Submucosal Gland Secretion and Mucociliary Clearance

Mucociliary clearance (MCC) is an important part of airway innate defense and is impaired in CF subjects and CF animal models. Five main components contribute to mucociliary clearance: airway submucosal gland secretion; airway surface epithelial secretion; airway surface epithelial fluid absorption; ciliary beat frequency; and airway diameter, controlled via airway smooth muscle tension. Dr. Nam Soo Joo discusses his research on submucosal gland secretion and mucociliary clearance in cystic fibrosis airways. Dr. Joo conducts his research in Dr. Jeff Wine's CF Lab at Stanford, with the support of CFRI.

CFTR, Submucosal Gland Secretion and Mucociliary Clearance (Audio)

Mucociliary clearance (MCC) is an important part of airway innate defense and is impaired in CF subjects and CF animal models. Five main components contribute to mucociliary clearance: airway submucosal gland secretion; airway surface epithelial secretion; airway surface epithelial fluid absorption; ciliary beat frequency; and airway diameter, controlled via airway smooth muscle tension. Dr. Nam Soo Joo discusses his research on submucosal gland secretion and mucociliary clearance in cystic fibrosis airways. Dr. Joo conducts his research in Dr. Jeff Wine's CF Lab at Stanford, with the support of CFRI.

Quantifying CFTR Ion Channel Function with Sweat Tests

Meagan Shinbashi, a researcher in Dr. Jeffrey Wine’s Cystic Fibrosis Research Laboratory at Stanford, demonstrates the utility of sweat tests in providing a near-linear readout of CFTR function. Meagan explains the importance of sweat tests in both a historical context as well as the future of these tests in monitoring the effectiveness of new treatments such as Triple Combination therapies and CRISPR Cas-9. Meagan further discusses how sweat tests can potentially be of use for patients with rare mutations in years to come.

Quantifying CFTR Ion Channel Function with Sweat Tests (Audio)

Meagan Shinbashi, a researcher in Dr. Jeffrey Wine’s Cystic Fibrosis Research Laboratory at Stanford, demonstrates the utility of sweat tests in providing a near-linear readout of CFTR function. Meagan explains the importance of sweat tests in both a historical context as well as the future of these tests in monitoring the effectiveness of new treatments such as Triple Combination therapies and CRISPR Cas-9. Meagan further discusses how sweat tests can potentially be of use for patients with rare mutations in years to come.

CF Fitness and Strength Building: An Interview with Taylor Lewis

Taylor Lewis, MS, runs the Cystic Fibrosis Fitness Institute in Northern California, where he helps develop personalized exercise and fitness programs for individuals with CF. He has worked with hundreds of people - both virtually and in person - to help them to build strength and endurance for the CF road. He is also an instructor through CFRI's Breathe In ~ Work Out CF Wellness Initiative, through which he teaches an online "Knowledge in Motion" class.

Filmed by Brandon Delgado.
Sound by Alana Ocampo

CF Community Voices is generously sponsored by Vertex Pharmaceuticals, Chiesi USA, and Gilead Sciences.