The CFRI CF Community Voices Podcast

CFRI hosted an online Town Hall Discussion on the film "Five Feet Apart," during which participants from around the U.S. joined in via Zoom. The discussion was broken into five topics. The full recording is available on our CF Community Voices playlist, but in this first episode, we explore the impact of the film upon the general public and the CF community.

Sponsored by Vertex Pharmaceuticals, Gilead Sciences and Chiesi USA.

CFRI hosted an online Town Hall Discussion on the film "Five Feet Apart," during which participants from around the U.S. joined in via Zoom to share their opinions and feelings about key themes of the movie.

Sponsored by Vertex Pharmaceuticals, Gilead Sciences and Chiesi USA.

Mucociliary clearance (MCC) is an important part of airway innate defense and is impaired in CF subjects and CF animal models. Five main components contribute to mucociliary clearance: airway submucosal gland secretion; airway surface epithelial secretion; airway surface epithelial fluid absorption; ciliary beat frequency; and airway diameter, controlled via airway smooth muscle tension. Dr. Nam Soo Joo discusses his research on submucosal gland secretion and mucociliary clearance in cystic fibrosis airways. Dr. Joo conducts his research in Dr. Jeff Wine's CF Lab at Stanford, with the support of CFRI.

Mucociliary clearance (MCC) is an important part of airway innate defense and is impaired in CF subjects and CF animal models. Five main components contribute to mucociliary clearance: airway submucosal gland secretion; airway surface epithelial secretion; airway surface epithelial fluid absorption; ciliary beat frequency; and airway diameter, controlled via airway smooth muscle tension. Dr. Nam Soo Joo discusses his research on submucosal gland secretion and mucociliary clearance in cystic fibrosis airways. Dr. Joo conducts his research in Dr. Jeff Wine's CF Lab at Stanford, with the support of CFRI.

Meagan Shinbashi, a researcher in Dr. Jeffrey Wine’s Cystic Fibrosis Research Laboratory at Stanford, demonstrates the utility of sweat tests in providing a near-linear readout of CFTR function. Meagan explains the importance of sweat tests in both a historical context as well as the future of these tests in monitoring the effectiveness of new treatments such as Triple Combination therapies and CRISPR Cas-9. Meagan further discusses how sweat tests can potentially be of use for patients with rare mutations in years to come.

Meagan Shinbashi, a researcher in Dr. Jeffrey Wine’s Cystic Fibrosis Research Laboratory at Stanford, demonstrates the utility of sweat tests in providing a near-linear readout of CFTR function. Meagan explains the importance of sweat tests in both a historical context as well as the future of these tests in monitoring the effectiveness of new treatments such as Triple Combination therapies and CRISPR Cas-9. Meagan further discusses how sweat tests can potentially be of use for patients with rare mutations in years to come.

Taylor Lewis, MS, runs the Cystic Fibrosis Fitness Institute in Northern California, where he helps develop personalized exercise and fitness programs for individuals with CF. He has worked with hundreds of people - both virtually and in person - to help them to build strength and endurance for the CF road. He is also an instructor through CFRI's Breathe In ~ Work Out CF Wellness Initiative, through which he teaches an online "Knowledge in Motion" class.

Filmed by Brandon Delgado.
Sound by Alana Ocampo

CF Community Voices is generously sponsored by Vertex Pharmaceuticals, Chiesi USA, and Gilead Sciences.

Taylor Lewis, MS, runs the Cystic Fibrosis Fitness Institute in Northern California, where he helps develop personalized exercise and fitness programs for individuals with CF. He has worked with hundreds of people - both virtually and in person - to help them to build strength and endurance for the CF road. He is also an instructor through CFRI's Breathe In ~ Work Out CF Wellness Initiative, through which he teaches an online "Knowledge in Motion" class.

Filmed by Brandon Delgado.
Sound by Alana Ocampo

CF Community Voices is generously sponsored by Vertex Pharmaceuticals, Chiesi USA, and Gilead Sciences.

Carol Conrad, MD, is the Medical Director of the Pediatric Lung and Heart-Lung Transplant Program, and Associate Professor of Pediatrics at Stanford University. While the number of children with cystic fibrosis requiring a double lung transplant are declining due to new therapies, each year, several children experience advanced end-stage lung disease requiring transplant. In this presentation, Dr. Conrad shares the history of pediatric transplant, the challenges and outcomes, and the future of transplant.

Filmed by Brandon Delgado and Alana Ocampo.

CF Community Voices is sponsored by Vertex Pharmaceuticals, Gilead Sciences and Chiesi USA. 

Carol Conrad, MD, is the Medical Director of the Pediatric Lung and Heart-Lung Transplant Program, and Associate Professor of Pediatrics at Stanford University. While the number of children with cystic fibrosis requiring a double lung transplant are declining due to new therapies, each year, several children experience advanced end-stage lung disease requiring transplant. In this presentation, Dr. Conrad shares the history of pediatric transplant, the challenges and outcomes, and the future of transplant.

Filmed by Brandon Delgado and Alana Ocampo.

CF Community Voices is sponsored by Vertex Pharmaceuticals, Gilead Sciences and Chiesi USA.